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James Alexander Little fonds
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James Alexander Little fonds

  • UTA 1480
  • Fonds
  • 1951-1996

The records in this accession document Dr. Alick Little’s research, teaching and publication activities over a forty-year medical career with the University of Toronto and two teaching hospitals, Sunnybrook and St. Michael’s in Toronto. Arranged i...

Little, James Alexander

APO C-II deficiency research

Series contains material documenting specific studies and general research within the Studies of Familial Apolipoprotein CII Deficiency project. Initiated in 1977, the project aimed to study family members with apolipoprotein C-II deficiencies in ...

Toronto McMaster Lipid Research Clinic

Series contains records related to specific studies administered by the Toronto McMaster Research Clinic in which Dr. Little was involved. Documentation covers the APO-CII Deficiency Study, the Population (Prevalence) Studies, and the Coronary Pri...

Population (Prevalence) Studies

Series contains records documenting research performed as part of the Toronto McMaster Lipid Research Clinics Population (Prevalence) Studies. Comprised of a number of individual studies, the project analyzed data from more than 8,200 subjects fro...

Annual reports, articles, correspondence

This subseries consists of annual reports on the Atherosclerosis study from 1953 to 1962, correspondence with Sunnybrook Hospital and U of T. officials as well as colleagues relating to the project’s operations and manuscripts and off prints of ar...

Summarized data

This series contains summarized data for each subject patient (coronary and control), arranged by decade. Includes name of patient, study number, data relating to physical condition at various dates, occupation, social class, etc.

Control and coronary patient case files

This series contains patient case files for male veterans in two groups: the study group of patients with evidence of coronary heart disease and the control group of ‘normal’ patients with no evidence of coronary heart disease. Patients ranged in...

Other studies

This subseries contains files relating to other studies conducted using data from this project. Between 1953 and 1956, Dr. Little and his team attempted to relate diet and the consumption of animal and vegetable fat. Files include some of the wor...

St. Michael’s Hospital

This series documents Dr. Little’s long association with St. Michael’s Hospital where he practised, researched and taught. The subject files contain correspondence, minutes of meetings, reports and other records relating to his activities on the ...

Grant applications

While the bulk of funding for the Lipid Research Project came from the US National Institutes of Health (see A2002-0009), funding for additional studies was sought from Canadian sources, mainly the OHF (the Ontario Heart Foundation and now the Ont...

Personal and general correspondence

This series contains general correspondence, curriculum vitae, letters of reference for clerical and professional staff broadly documenting his activities as teacher, administrator and author, as well as other professional activities. Corresponde...

Articles, abstracts, talks, papers, lectures

During his long career Dr. Little wrote extensively on the results of his research. Many of these were collaborative products with colleagues, research associates and students and were published in scholarly scientific and other publications. Amo...